Evaluation of enzymes inhibition activities of medicinal plant from Burkina Faso.
- Pak J Biol Sci. , 14 (2) : 99-105
Résumé
The aim of the present study was to evaluate some enzymes inhibitory effects of 11 plant species belonging to 9 families from Burkina Faso. Methanolic extracts were used for their Glutathione-s-transferase (GST), Acetylcholinesterase (AChE), Carboxylesterase (CES) and Xanthine Oxidase (XO) inhibitory activities at final concentration of 100| rg mL_1. The total phenolics, flavonoids and tannins were also determined spectrophotometrically using Folin-Ciocalteu, A1C13 and ammonium citrate iron reagents, respectively. Among the 11 species tested, the best inhibitory percentages were found with Euphorbia hirta, Sclerocarya birrea and Scoparia dulcis (inhibition 40%) followed by Annona senegalensis, Annona squamosa, Polygala arenaria and Ceratotheca sesamoides (inhibition 25%). The best total phenolic and tannin contents were found with S. birrea with 56.10 mg GAE/100 mg extract …
Mots-clés
Polyphenolic compounds, glutathion-S-transferase, Acetylcholinesterase, Carboxylesterase