High nevirapine levels in breast milk and consequences in HIV-infected child when initiated on antiretroviral therapy

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Résumé

Nevirapine remains used in resource-limited areas for
both the prevention of mother-to-child transmission and
maternal antiretroviral therapy (ART). As breastfeeding
practice is prolonged in Africa [1], breastfed infants HIVinfected
while their mother is receiving ART may have
high risk of drug resistance, which may limit their future
treatment options. We evaluate the intake of nevirapine
through breastmilk and its consequences for their
breastfed HIV-infected children while their mother
was receiving a nevirapine-based ART.

Mots-clés

NEVIRAPINE, BREAST MILK, CONSEQUENCES